Teammate Victor Oladipo added 15 points, nine rebounds, five steals and three blocks. He also spearheaded a defense that held the Blue Devils' Kyle Vinales, the nation's leading scorer, to 7 points on 3-for-15 shooting. Vinales entered the game averaging 25.9 points.
Christian Watford added 21 points for IU.
However, the Blue Devils (4-4) got 40 points and seven rebounds from guard Matt Hunter.
IU (9-0) gets a week off for finals before playing Butler next Saturday as part of the Crossroads Classic. Notre Dame will play Purdue in the other game at Indianapolis' Bankers Life Fieldhouse.
The Butler game should mark the first appearance of the season for freshman Hanner Perea and Peter Jurkin. They were suspended for the first nine games for receiving impermissible recruiting benefits.
IU's first-half dominance was marred by an apparent left knee injury to reserve guard Austin Etherington. He hit the floor hard and instantly shouted out in pain. IU's medical staff quickly got to him, and just as quickly called for a stretcher. His teammates lifted him onto the stretcher. Etherington was in obvious pain, but pointed to the crowd as he was transported off the court for further evaluation.
In two minutes Etherington had one rebound and two fouls.
IU's full-throttle pace took about seven minutes to wear down Central Connecticut State. Then came a 21-2 run that left the Blue Devils reeling. By halftime, the Hoosiers led 53-34.
Oladipo led another Indiana surge to start the second half with a steal and a dunk. After 90 seconds, Blue Devils coach Howie Dickenman had seen enough and called a timeout, but it wasn't nearly enough.