"I lost my son three days ago. He's alive only because of a machine," Matias said. "My son is not alive. My son is only alive for the people who love him," she added.
She said at a news conference Friday night that she was waiting only for Camacho's three other sons, who were expected to arrive from the U.S. mainland early Saturday. "Until they arrive, we will not disconnect the machine," Matias said.
The former champion's mother has the final say in the matter, but his eldest son, Hector Camacho Jr., said he wanted to keep his father alive.
"He's going to fight until the end. My father is a boxer," the son said.
Doctors had said Camacho was clinically brain dead from a shooting Tuesday night in his hometown of Bayamon.
Camacho was shot as he sat in a car with a friend, 49-year-old Adrian Mojica Moreno, who was killed in the attack. Police spokesman Alex Diaz said officers found nine small bags of cocaine in the friend's pocket and a 10th bag open inside the car.
Police reported no arrests and said investigators continued to look for potential witnesses.
Camacho battled drug, alcohol and other problems throughout his life. He was sentenced in 2007 to seven years in prison on burglary charges, but a judge eventually suspended all but one year of the sentence and gave Camacho probation. He wound up serving two weeks in jail after violating that probation. A wife also filed domestic abuse complaints against him twice before their divorce.