The telecast will benefit the American Red Cross and be shown on NBC and its cable stations including Bravo, CNBC, USA, MSNBC and E! Other networks are invited to join in.
The concert will be hosted by Matt Lauer. It will air at 8 p.m. Eastern and will be taped-delayed in the West.
Other performers include Christina Aguilera, Sting and Jimmy Fallon.
The telethon will be broadcast from NBC facilities in Rockefeller Center in New York City.